Thursday, December 9, 2010

Antioxidants May Reduce Inflammation in Alzheimer’s Disease

Previous studies have reported that high levels of homocysteine, a pro-inflammatory protein component, are associated with dementia or Alzheimer’s Disease.


In an effort to determine if antioxidants reduced the inflammation associated with such high homocysteine levels, J.M. Morillas-Ruiz, from Catholic University of San Antonio (Spain), and colleagues enrolled 100 women to participate in a double-blind controlled clinical trial.


Fifty-two of the women were considered generally healthy (no Alzheimer’s) and served as the control group, while the other 48 were diagnosed with Alzeimer’s disease (24 women with early-onset and 24 with moderate Alzheimer’s).


Each of the women was randomly assigned to one of two interventions: Drink an antioxidant beverage rich in polyphenols, or receive a placebo drink, for the eight-month long study. The antioxidant beverage was formulated using apple and lemon concentrate juice, apple and green tea extracts, and vitamins B and C.


The team found that those women who consumed the antioxidant-rich drink experienced an attenuation of homocysteine increase, as compared to the placebo group.


As well, in the subjects with moderate Alzeimer’s disease, the antioxidant beverage was associated with lower average homocysteine level, as compared to the placebo group. The researchers conclude that: “The regular ingestion of polyphenols contained in an antioxidant beverage may decrease [total homocysteine] plasmatic concentrations in Alzheimer's patients.”


From: http://www.worldhealth.net/news/antioxidants-may-reduce-inflammation-alzheimers-di/


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Study Shows Vitamin A Supplements Reduce Deaths Caused by Measles, Diarrhea

The double-mindedness of the health authorities never ceases to amaze me.

Only this past summer we saw a number of medical experts quoted in a heavily biased Reader’s Digest article assuring the public there is very little benefit at all from taking vitamins, minerals, herbs and other supplements.

After that, a rash of studies were published demonstrating amazing effectiveness of Vitamin D in preventing scores of diseases including Parkinson’s disease, flu, breast cancer, bone loss, heart disease, depression, faltering memory and more…

…equally amazing effectiveness against heart disease, diabetes and cancer was reported for the nutritional supplement Reservatrol…

…and we saw an Oxford University study demonstrating that high doses of folic acid, vitamin B6 and B12 slash brain shrinkage by up to 53%!

Now, we have this new study by Cochrane researchers demonstrating the fact that Vitamin A reduces childhood deaths from disease by a whopping 24%, and recommending that children in underdeveloped countries where disease is rampant be given regular Vitamin A supplements.

Well…which is it? Either vitamins, minerals, herbs and other supplements are worthless, or they are beneficial.

What do you think?

-- Spencer


Study Shows Vitamin A Supplements Reduce Deaths Caused by Measles, Diarrhea

Vitamin A supplements are still an effective way to reduce childhood death and disease.

A new study by Cochrane researchers strongly endorses the continuation of vitamin A supplementation programs, which reduce the incidence of measles and diarrhea and ultimately save lives.

Vitamin A deficiency is a common problem in low and middle income countries. People whose diets do not include enough of the vitamin may have impaired body functions, and be more susceptible to blindness, infection and early death.

The World Health Organization (WHO) recommends vitamin A supplements for pregnant mothers and children. However, controversies have recently been raised regarding the effectiveness of vitamin A supplementation programmes in developing countries.

The 43 trials included in the review involved 215,633 children between six months and five years of age. All except one trial used the standard dose of vitamin A as recommended by the WHO.

Overall, giving vitamin A capsules reduced the risk of death from any cause by 24% compared to placebos or usual treatment. This equates to saving the lives of almost a million vitamin A deficient children a year.

The review suggests that much of the beneficial effect vitamin A supplementation in developing countries may be related to prevention of measles and diarrhea.

"Giving vitamin A is associated with a reduction in the incidence of diarrhea and measles, as well as the number of child deaths due to these diseases," said Zulfiqar Bhutta, Chairman of the Division of Women and Child Health at Aga Khan University in Karachi, Pakistan and the senior reviewer of the project.

"However, the effects of supplementation on disease pathways are not well understood, so this could be a focus for further studies."

The researchers strongly recommend continuation of vitamin A supplementation programs in children under five, but recognise that this it is not a permanent solution to the problem of vitamin A deficiency.

"Fortification, dietary diversification, food distribution programs and horticultural developments such as home gardening and bio-fortification may provide more permanent relief," said Bhutta.

"For example, vitamin A content could be increased in staples such as rice or growers may aim to promote use of biofortified foods such as orange sweet potato."

From: http://www.npicenter.com/article/Research/Vitamin-supplements-reduce-deaths-caused-by-measles-and-diarrhea.aspx

Source: Wiley-Blackwell
December 09, 2010 12:01 AM


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Wednesday, December 8, 2010

Can Drinking Beet Juice Help Protect Against Dementia?

Beet juice to beat dementia? Maybe.

We know from prior research that beet juice can lower blood sugar.


Now a study published online—November 2010 at Nitric Oxide: Biology and Chemistry—reveals that beet juice can do even more: open up blood vessels and increase blood flow/oxygen to a critical region of the brain.


Researchers at the Translational Science Center (Wake Forest University, Winston-Salem, North


Carolina) administered a “high vs. a low nitrate diet” to older adults (mean age 74.7). Those with a high-nitrate diet consumed 16 ounces of beet juice with breakfast and followed specific diets for lunch, dinner and snacks.


Subjects underwent 10-hour fasts and strategic MRIs that recorded blood flow in the brain.


Hopeful findings: Consuming a high-nitrate diet increased blood flow to white matter of the brain’s frontal lobes (region linked to degenerative cognitive conditions).


“These are the areas in the brain that become poorly perfused as you age, “says Daniel Kim-Shapiro, Director of the Center, “and that’s believed to be associated with dementia and poor cognition.”


From: http://www.cenegenics.com/pdf_files/newsletter_dec.pdf


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Can Vitamin B12 Help Prevent Alzheimer’s Disease?

An October 2010 issue of Neurology, from the American Academy of Neurology, published findings from a small, preliminary study conducted by the Karolinska Institute in Stockholm, Sweden.

According to researchers, “vitamin B12 and related metabolites may have a role in Alzheimer’s disease”—an important finding since a vitamin B12 deficiency is a “common condition” in the elderly.


Investigating homocysteine levels (if elevated, associated with strokes) and levels of an active protein in B12 (holotranscobalamin) that can reduce homocysteine blood level. Their seven-year follow-up revealed that with every small increase of homocysteine, the risk for Alzheimer’s shot up 16%.


More study is needed, yet a case is being made for a diet rich in vitamin B12 to ward off neurodegenerative disease.


Top Food Sources of Vitamin B-12, Per 100g Serving:


• fish (mackerel, herring, salmon, tuna, cod,sardines, trout, bluefish) - 317% RDA (mackerel)

• beef - 103% RDA (lean, fat-trimmed chuck)

• lamb - 62% RDA (shoulder cut)

• cheese - 56% RDA (swiss cheese), 40% RDA (gjetost), 39% RDA (mozzarella), 38% RDA (parmesan), 35% RDA (tilsit)

• eggs - 33% (chicken, raw yellow), 122% RDA (goose egg), 63% (duck egg)


From: http://www.cenegenics.com/pdf_files/newsletter_dec.pdf


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Luteolin-rich Foods Shown to Reduce Brain Inflammation, Boost Memory

According to a study in the October 2010 Journal of Nutrition, loading up on luteolin-rich foods is a first smart step toward a healthier working memory.


Luteolin is a biochemical agent that can significantly reduce inflammation, thanks to its potent antioxidant activities . . . not to mention its other functions as a supernutrient (bioflavonoid), carbohydrate metabolism promoter, immune system modulator and free radical scavenger.


Rodney Johnson, lead researcher of the University of Illinois study and director of the university’s Division of Nutritional Sciences, states that inflammation in the brain “appears to be a key contributor to age-related memory problems.”


His research investigated microglial cells—immune cells in the brain/spinal cord—that when instigated by infection release cytokines, causing a series of chemical shifts. Sleepiness, not-as-sharp memory, depressed attitudes and appetite loss result from illness stoked by these inflammatory cytokines.


Per Johnson, his team previously found that during normal aging, “microglial cells become dysregulated and begin producing excessive levels of inflammatory cytokines.”


The researchers believe that is what ultimately contributes to cognitive aging and what also is a predisposing factor for the development of neurodegenerative disease.


The study, according to a University of Illinois site article, is the first to “suggest luteolin improves cognitive health by acting directly on the microglial cells to reduce production of inflammatory cytokines in the brain.”

Memory restored to earlier age levels. The study’s subjects were mice—older mice typically have high levels of inflammatory molecules in their hippocampus, a key brain region for memory and spatial awareness.


But the aged mice on a luteolin diet . . .


• performed better on “learning and memory task” than peers


• had lower levels of inflammatory cytokines, more like those of younger adult mice


Johnson says that providing a luteolin diet to the older mice “reduced inflammation in the brain and at the same time restored working memory to what was seen in young cohorts.”


With that, Johnson and his team believe “dietary luteolin accesses the brain and inhibits or reduces activation of microglial cells and inflammatory cytokines they produce. The anti- inflammatory effect is likely the mechanism which allows their working memory to be restored to what it was at an earlier age.”


What does the data suggest for us?


Per Johnson’s research: Consuming a healthy diet has the potential to reduce age-associated inflammation in the brain, which can result in better cognitive health.

So eat up your fill of these luteolin foods and herbs:
  • celery hearts (higher than celery stalk)
  • peppers (hot)
  • rutabagas
  • spinach
  • parsley
  • thyme
  • peppermint
  • basil
  • artichoke leaves
  • rosemary
  • sage
  • peppers (sweet)
  • olive oil
  • lemons
  • water spinach
  • lettuce
  • kohlrabi
  • kale, Chinese
  • gourd, dishcloth
  • celeriac
  • cauliflower
  • brussel sprouts
  • chamomile tea
  • beets

From: http://www.cenegenics.com/pdf_files/newsletter_dec.pdf



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Meet Steve Barwick





Monday, November 22, 2010

Red Wine as Effective as Popular Drug in Fight Against Type II Diabetes

Drinking a small glass of red wine every day can help treat diabetes, research has found.

Potent “super-food” compounds found in the wine can work as well as a daily dose of medication for people with Type 2 diabetes.

The discovery will come as welcome news to the 2.5 million people in Britain suffering from this form which can cause strokes, heart attacks and blindness.

Scientists discovered antioxidants in red wine can be just as effective as a daily dose of a combative drug.

The polyphenols – biologically active compounds in the wine – operate in a similar way to the drug rosiglitazone which is now banned.

The research was carried out before the ban came into effect.

Experts from Vienna’s University of Natural Resources and Applied Life Sciences found that a 125ml glass each day was enough to provide people with Type 2 diabetes with their daily dose of medication.

As well as the 2.5 million sufferers, a million more are thought to be living undiagnosed with the condition. Type 2 diabetes normally develops in middle age as a result of obesity or an unhealthy lifestyle.

The scientists, whose study is published in the Royal Society of Chemistry journal Food and Function, said the recommended daily dose for treating Type 2 diabetes using rosiglitazone is between 4mg and 8mg.

The team said 100ml of the tested red wines was equivalent to 1.8-18mg of rosiglitazone. It adds to the mounting evidence about the health benefits of a glass or two of red wine.

Rosiglitazone, also known as Avandia and made by GlaxoSmithKline, was taken by 100,000 people in the UK until it was recently banned because of increased risk of heart problems.

But Dr Iain Frame, director of research at Diabetes UK, said: “It is very difficult to see how this limited research will have any benefit to people with Type 2 diabetes. It is a basic study into the chemistry of red wine and has no clinical relevance at this stage. The researchers have made an astonishingly bold suggestion.”

Cheers! Here's to good health

- One 175ml glass a day can lower the risk of heart attack, helping to open blood vessels to prevent clots forming

- It also gives the daily required dose of iron (10mg for men, 15mg for women) and can help bone density in both sexes.

- Red wine has also been shown to preserve eyesight - a compound called reservatrol protects against the formation of damaged blood vessels which can cause blindness

- It can also protect against cancer due to the high polyphenol content in red grape skins

- Research indicates that moderate red wine consumption can have a positive effect on cholesterol levels and blood pressure, the so-called “French” effect

From: http://www.express.co.uk/posts/view/212962/How-red-wine-fights-diabetes

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Wednesday, November 3, 2010

How To Treat a Cold Without Drugs

Over-the-counter cold medicines won’t heal a winter virus faster – and some will even prolong it. But the best remedies don’t need a trip to the drug store , says Kate Hilpern


The average adult gets two to five colds a year. Children suffer the worst, with seven to 10 a year.


The news today is that scientists may in the near future be able to cure colds and other viruses. But for now, only the immune system can cure a cold and in most cases, it takes four to seven days.


Conventional medicines might provide relief from symptoms, but don’t work against the virus or help our immune system throw off the infection. Some don’t even do that. Standard cough medicines, for instance, have been found to be no better than placebo. Some doctors say suppressing coughs can be a bad thing since they are nature’s way of getting rid of respiratory debris. The good news is, you can take action to help your cold without even going out.


Inhale steam


“The common cold is a collection of different viruses and your immune system’s response to them causes the symptoms of inflamed nasal passage and lining of the sinuses – which causes sneezing, runny nose and sore eyes,” explains Professor Steve Field, chairman of the Royal College of General Practitioners. “The best way to reduce this inflammation is to keep the nasal passages clear. Steam is wonderful at achieving this.”


Put a towel over your head and inhale steam from a bowl of boiling water, ideally using drops of a plant oil such as eucalyptus or olbas oil for added relief. “Or take a nice hot shower with plenty of steam or sit in a really steamy bathroom – particularly good for children,” adds Professor Field.


Have a hot drink


Hot drinks work wonders, says Professor Ron Eccles, director of the Common Cold Research Centre at Cardiff University. One study found the effects of a hot fruit drink on nasal airflow and common cold and flu symptoms were surprisingly positive. “The hot drink provided immediate and sustained relief from symptoms of runny nose, cough, sneezing, sore throat, chilliness and tiredness,” he says.


Drinks with slightly bitter flavours are particularly beneficial. Many doctors suggest hot water with honey (a mild antiseptic), grated ginger (anti-inflammatory) and fresh lemon (tastes nice but the claim that vitamin C can cure colds is still unproven).


Eat chicken soup – or some curry


The brothy goodness of home-made soup has everything going for it, particularly if it’s chicken. It flushes out the nasal passages with its aromatic steaming and offers hydration and comfort.


There are also claims that chicken has anti-viral properties, particularly if the skin is left in, and in 2000, scientists at the University of Nebraska Medical Centre in Omaha found that some components of chicken soup inhibit neutrophil migration, which may have an anti-inflammatory effect that could perhaps lead to a temporary easing of the symptoms of illness.


A cold is a good excuse for a hot curry, says Professor Eccles. “Spicy food and drink promotes salivation and airway mucus secretions that soothe coughs and sore throats,” he explains.


Take it easy


Take one or preferably two days away from the office, insists Dr Beata O’Donoghue, sleep consultant at the London Clinic. You will save others from your germs and a cold can be the body’s way of telling us to take a break. She says: “Listen to your body. We do not repair ourselves during wakefulness, but during sleep.” Professor Field agrees: “With any virus that involves inflammation, even light exercise can be harmful, especially as we get older.”


Drink water


“When the body is fighting infection, it becomes dehydrated,” says Dr Rob Hicks, GP and author of Old-fashioned Remedies From Arsenic to Gin. “You need plenty of fluids.” Provided it’s not alcohol anything palatable is acceptable, says Hicks. Others disagree. Soft drinks contain high levels of sugar, which means they are absorbed much more slowly than water so they don’t hydrate the body as quickly. Really high-sugar drinks cause a rapid rise in blood sugar level, followed by a sudden dip, making you feel worse.


By the time you feel thirsty, dehydration has set in – so drink regularly.


Raid your store cupboard


“Nutrients with potential immune-boosting properties include vitamin A (in eggs, milk and orange fruit and vegetables such as carrots and apricots), vitamin E (nuts, grains, vegetable oils and wheatgerm) and selenium (in brazil nuts, seafood, meat, and poultry),” says Sara Stanner of the Nutrition Society. And try to eat as much garlic as possible because of its antimicrobial action.


De-stress


Everyday life pressures can make you more susceptible, says Professor Eccles: “Experiments on volunteers show they are more likely to become infected if they have recently suffered problems.” Stress has long been associated with the suppression of general resistance to infection.


Wrap up warm


“Granny was right as far as wrapping up warm is concerned, in the prevention of colds,” says Dr Rob Hicks. “When the nostrils get cold, the immune system functions less efficiently. And if your temperature falls, your immune system is not as efficient.”


You could also try...


* Blowing your nose regularly rather than sniffing the mucus back into your head. Ideally, press a finger over one nostril while you blow gently to clear the other.


* Gargling can moisten a sore throat to bring temporary relief. Try a teaspoon of salt dissolved in warm water, four times daily. Or use honey, popular in folk medicine.


* Sleeping with an extra pillow will help with the drainage of nasal passages.


Tuesday, 2 November 2010


From: http://www.independent.co.uk/life-style/health-and-families/features/how-to-treat-a-cold-without-drugs-2122568.html


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